World’s first 1-channel 10 MHz current amplifier for high-bandwidth measurements. Suitable for solid-state nanopores and nanoparticle detection.
Why to choose the Nanopore Reader 10 MHz?
Bandwidth – The high bandwidth allows to investigate electrophysiological events lasting less than hundreds of nanoseconds
Versatile – The amplifier is suitable for experimental activities such as, DNA translocation, single molecule detection or channel recordings…
User friendly – Tools free, just insert the flow cell in the device
They say about us – “… the full 10 MHz bandwidth and 40 Msps sampling rate, combined with ±100nA of dynamic range, is what sets this instrument apart from others as it offers an unprecedented opportunity to study details of fast biomolecular translocations using the entire range of solidstate nanopore chips”
Read the full review from Northern Nanopore Instruments here.
Nanopore Flow Cell
A microfluidic system serving as the interface between the nanopore chip and the current reader. Depending on your needs, you can choose between different materials. The nanopore chip can be rapidly changed without tools and the flow cell is reusable.
Nanopore Chip: Vertical
Chambers Volume: 10 µl min – 60 µl max
Flowcell Materials: PMMA or Teflon
Replaceable External Silver Wires
Nanopore Chip not Included, buy it from Norcada
Nanopore Chip Compatibility: Square 4×4-5×5 mm², 200-700 µm thick and round 3×3 mm², 200 µm thick
Reusable Flow cell
More Information
- Open input (RMS) noise: 525 pA rms @ 10MHz; 160 pA rms @ 1MHz; 40 pA rms @ 100 kHz
- Noise 10MΩ//2.5pF model cell: 1200 pA rms @ 10MHz; 200 pA rms @ 1 MHz; 45 pA rms @ 100kHz
- Current ranges: ±100nA (Gain 10MΩ)
- Voltage stimulus range: ± 1600 mV
- Max available bandwidth: 10 MHz
- Max sampling rate: 40 Msps
- USB type C connector
- Size & Weight: Headstage 77 x 87 x 40 mm, 300 g; Data acquisition unit 64 x 100 x 29 mm, 270 g
User Guides
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- Nanopore Reader 10MHz Connection Diagram
- Nanopore Reader 10MHz Manual Calibration
- Nanopore Flowcell for 5×5 and 4×4 mm Nanopore Chips: Assembly and Cleaning procedure
- Nanopore Flowcell for 5×5 mm Nanopore Chips: Assembly and Cleaning procedure
- Nanopore Flow Cell for 3 mm Round Nanopore Chips: Assembly and Cleaning procedure
Technical Guides
- HyperXtract: Strategic Platform for Optimizing High-Bandwidth Nanopore Data Extraction Performance; K Gussenhoven, D Amarasekara, J Saharia, YM Nuwan DY Bandara; Chemrxiv, 2025
- Unraveling RNA Conformation Dynamics in Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episode Syndrome with Solid-State Nanopores; S Namani, K Kavetsky, CY Lin, S Maharjan, HB Gamper, NS Li, JA Piccirilli, YM Hou and M Drndic, ACS Nano, 2024
- Coupled nanopores for single-molecule detection; YC Chou , CY Lin , A Castan, J Chen , R Keneipp, P Yasini, D Monos & M Drndić; Nature Nanotechnology, 2024
- High Accuracy Protein Identification: Fusion of Solid-State Nanopore Sensing and Machine Learning; Dutt, S., Shao, H., Karawdeniya, B., Bandara, Y. M. N. D. Y., Daskalaki, E., Suominen, H., Kluth, P., Small Methods 2023, 2300676
- Ultrafast Polymer Dynamics through a Nanopore; Chih-Yuan Lin, Riley Fotis, Zehui Xia, Kyril Kavetsky, Yung-Chien Chou, David J. Niedzwiecki, Michele Biondi, Federico Thei, and Marija Drndić. Nano Letters 2022 22 (21), 8719-8727
- Silicon Nitride Nanopores Formed by Simple Chemical Etching: DNA Translocations and TEM Imaging; Zehui Xia, Andre Scott, Rachael Keneipp, Joshua Chen, David J. Niedzwiecki, Brian DiPaolo, and Marija Drndić. ACS Nano Article ASAP
Custom device development
With our custom ASIC design technology we can help you configure specific tools and solutions for your applications.
Let us know how we can help you design the tools and software you need.